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  • 6. Does DEHP pose risks to human health?

     · The human population may be exposed to DEHP by swallowing it, for example in food, by breathing it in, and, to a much lesser extent, by skin contact. Risks are assessed by dividing worst-case exposures to the exposures at which no harmful effects were observed in animal studies. This gives the margin of safety (MOS).

  • Evidence of DEHP harm to reproduction, fertilityEHN

     · Evidence of DEHP harm to reproduction, fertility Manufacturers add phthalates like DEHP to plastic products to increase flexibility and reduce brittleness. Some medical products such as IV bags and tubing can contain up to 40 percent DEHP by weight, according to an analysis by Health

  • What is the best alternative to DEHP for medical-grade PVC

     · While phthalate esters such as DEHP are the most widely used plasticizers for flexible PVC medical compounds and have been for 50 years, issues concerning their possible effects on human health have caused some device manufacturers to consider

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  • Hospitals Demand Switch to PVC- and DEHP-Free Devices

     · CHW is a network of 40 hospitals and medical centers located in California, Arizona, and Nevada. As it learned about the physical and environmental effects of products containing PVC and DEHP, CHW began advocating for alternative products from its vendors. Other hospitals have also called for a switch to PVC- and DEHP-free devices.

  • Ethiopian Health SystemHealth Care in Ethiopia Health

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     · secondary excreted DEHP metabolites) suggest a current median exposure of 2 to 5 µg/kg bw/d, whereas the 95th percentile is estimated to be between 6 and 17 µg/kg bw/d. Use of PVC medical devices may lead to a higher exposure to DEHP than everyday sources affecting the general population. Several procedures such as exchange transfusion of

  • Regulation of DEHP Health Care Without Harm

    Regulation of DEHP. In the last few years, a number of government agencies and expert panels in Europe, the US, Canada, and Japan have reviewed the safety of DEHP, used to soften PVC medical devices. Each of these agencies and expert panels has found that DEHP exposure from some medical procedures may pose a risk to patients' health.

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  • Phthalate freeIntersurgical

    The availability of safer alternatives to PVC products means the prudent course of action for NICU’s could be to introduce DEHP/PVC-free products. Plasma phthalate levels in pubertal gynecomastia. Use of di (2-ethylhexyl)phthalate-containing medical products and urinary levels of mono (2-ethylhexyl)phthalate in neonatal intensive care unit

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  • Adopt some DEHP-free alternatives immediately.

     · In January 2002, Health Canada released the Final Report of the Expert Advisory Panel on DEHP in Medical Devices.1 Below is a summary of the Expert Panel’s findings. The Panel made recommendations based on a 2001 Health Canada review entitled “DEHP in Medical Devices An Exposure and Toxicity Assessment,”2 and external studies,


     · to ensure that DEHP-free blood packs provide blood components of equivalent qualityto thosecurrentlyin use.” Sanquin –“Bloodpack procurement exercises are complex and subject to tendering rules, therefore can take several years. Prior to this, at least five years’ worth of development work, validation and clinical trials would be

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  • Sample List of PVC/DEHP-Free Products in Health Care

     · Page 1 of 33 Key PVC content, DEHP free cbw = confirmed by website cbc = confirmed by contact with company How confir med Category Manufacturer Telephone #

  • Why 180 Medical Carries Catheters Without DEHP180 Medical

    DEHP-Free Hydrophilic and Pre-lubricated Catheters. For questions requiring medical advice regarding the potential health effects of DEHP, please talk to your doctor or another qualified medical professional. Call Toll-Free (877) . Request Free Samples. Join the 180 Community.

  • Vancive Medical Technologies To Offer DEHP-Free Products

     · Plasticizer-Free Material. Vancive Medical Technologies supports medical device manufacturers with technical assistance and advanced materials that anticipate possible rules on DEHP use, including InteliShield barrier film. The film is designed with a novel combination of plastics that are devoid of PVC and plasticizers including DEHP.

  • Non-DEHP PVC and Medical Devices Thought Leadership

    By Larry Wallace. The story around PVC (polyvinyl chloride) and DEHP (di-2ethylhexyl phthalate)-based PVC in medical devices has been well told. PVC has been a staple in medical products and medical devices since the second world war and today still really has no equal in its widespread use and application. Nevertheless, about thirty years ago

  • Toxic Effects of Di-2-ethylhexyl Phthalate An Overview

     · Di-2-ethylhexyl phthalate (DEHP) is extensively used as a plasticizer in many products, especially medical devices, furniture materials, cosmetics, and personal care products. DEHP is noncovalently bound to plastics, and therefore, it will leach out of these products after repeated use, heating, and/or cleaning of the products. Due to the overuse of DEHP in many products, it enters and

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  • Is DEHP in Catheters Harmful?180 Medical

    Yes, 180 Medical is committed to carrying a wide variety of high-quality catheter products, including DEHP-free catheters. Because we want our customers to have a catheter that fits their individual needs and preferences, we make it a point to offer plenty of options from all the top brands on the market.

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  • FDA Pushes Labeling of Medical Devices That Contain DEHP

     · FDA Pushes Labeling of Medical Devices That Contain DEHP. The Food and Drug Administration (FDA) is recommending that manufacturers label medical devices made with di- (2-ethylhexyl)phthalate (DEHP), a chemical used to soften polyvinvyl chloride (PVC) plastic. The FDA's draft guidance also recommends that medical device manufacturers consider

  • Human Health Toxicity Risk Assessment of DEHP in

     · The extent to which DEHP is released from PVC medical devices is a function of the lipophilicity of the fluid that comes into contact with the device, length and surface area of the tubing used, flow rate and temperature. There is also wide variability in reported rates of DEHP extraction from medical tubing for the various medical devices.

  • Non-PVC, Non-DEHP IV Solutions ICU Medical

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